Rossi AP, et al. - This study was undertaken to determine if multiple weight cycles (or “yo-yo” diets) in adulthood independently forecast lower muscle mass and decreased strength, along with the possible implications of sarcopenia in obese adults. Participants in the study were 60 males and 147 females with obesity (mean BMI 37.9 ± 6.0 kg/m²; mean age 52.6 ± 12.4 years). Participants were classified as non-weight cyclers, mild weight cyclers, and severe weight cyclers. Investigators found that participants experiencing a greater number of weight cycles during their lives have lower muscle mass and muscle strength as assessed via handgrip. Data reported that the risk of developing sarcopenia was 5.2 times higher for severe weight cyclers. Findings suggested an association of weight cycling with lower muscle mass and strength in adults with obesity and a greater likelihood of developing sarcopenic obesity.