Wang F, et al. - Through a retrospective study of 65 patients with single-level upper lumbar disc herniation (ULDH), who underwent surgery between January 2012 and December 2016, researchers examined the association between symptomatic ULDH and wedge-shaped vertebrae (WSV). The incidence of WSV in the ULDH group was more in comparison with the lower lumbar disc herniation group. Statistically important variations in WSV, wedging angle of the vertebrae (WAV), and thoracolumbar kyphotic angle (TL), among the two groups, were found. On the basis of multivariate logistic regression analysis, WAV and TL were independently related to ULDH. The cutoff values of WAV and TL were 5.35° and 8.35°, which were significantly correlated with ULDH. Hence, for ULDH, the WSV is an independent risk factor. The predictors for ULDH were WAV > 5.35° and TL > 8.35°. It should be remarked that the patients with vertebral wedge deformation combined with thoracolumbar kyphosis have a greater risk of ULDH.