Del Pinto R, et al. - Given an inverse link between hypovitaminosis D and blood pressure (BP) is supported by observational evidence, and since there is downwards redefinition of hypertension treatment targets and the requirement to better recognize people at greater risk for uncontrolled BP, researchers examined the link of serum vitamin D levels with the definition of uncontrolled BP according to European guidelines in adults who were treated for hypertension. From treated hypertensive adults aged at least 18 years with available serum 25 (OH)D measurements, they obtained and retrospectively examined cross-sectional, nationally representative data. A higher mean BP and 25–29% higher risk of uncontrolled BP was observed in treated hypertensive adults with vitamin D deficiency vs those exhibiting vitamin levels at least 75 nmol/l. These findings were verified across age, gender, and racial/ethnic strata. Link of vitamin D insufficiency with higher BP by 0.5/2.4 mmHg, but not with an enhanced risk of uncontrolled hypertension, was also identified. Experts concluded that 25 (OH)D levels might suggest host-specific characteristics associated with poor BP control. The effort to utilize a biomarker of exposure as an indicator of the requirement for treatment risks to be misleading.