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Visual acuity outcomes in diabetic macular edema with fluocinolone acetonide 0.2 μg/day vs ranibizumab plus deferred laser (DRCR Protocol I)

Ophthalmic Surgery, Lasers and Imaging Sep 25, 2018

Singer MA, et al. - Researchers assessed the visual outcomes of the FAME study (0.2 μg/day fluocinolone acetonide [FAc]) vs the Protocol I (0.5 mg ranibizumab plus deferred laser) via the area under the curve (AUC) analysis method. They noted that FAc and ranibizumab plus deferred laser were similar, but FAc allowed for fewer injections in pseudophakic and chronic diabetic macular edema (DME) subgroups. Nonetheless, ranibizumab plus deferred laser and FAc were not found to be significantly different for subgroups of pseudophakic eyes, eyes with chronic DME, and pseudophakic eyes with chronic DME.

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