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Use of inflammatory biomarkers and real-time cardiac catheterisation to evaluate the left ventricular diastolic function in patients with diastolic heart failure

Heart, Lung, and Circulation Aug 01, 2020

Xu L, Yan J, Zhang F, et al. - In the present study, the researchers sought to explore the association between interleukin (IL)-17 and left ventricular diastolic dysfunction (LVDD), and examine the prognostic value of IL-17 among patients with normal left ventricular ejection fraction (LVEF). In total, 120 patients with normal LVEF had left ventricular (LV) catheterisation for LV end-diastolic pressure measurement and routine echocardiography. In non-heart failure (HF) patients with LVDD, the levels of IL-17 and IL-6 from the systemic blood were significantly increased. The evaluation of LVDD by measuring the combination of IL-17 and IL-6 may provide a valuable prognosis for non-HF patients with LVDD.

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