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Use of corneas from septic donors for descemet membrane endothelial keratoplasty

Cornea Dec 04, 2020

Vasiliauskaitė I, de Jong M, Quilendrino R, et al. - Researchers conducted this retrospective study to assess the suitability of corneas from septic donors for transplantation by analyzing the discard rate in the eye bank and the clinical outcome of Descemet membrane endothelial keratoplasty (DMEK) utilizing organ-cultured corneal grafts from septic vs nonseptic donors. They involved 1,554 corneas of which 456 corneas (29%) were from septic and 1,072 corneas (69%) from nonseptic donors [for 26 corneas (2%) sepsis status was unknown]. According to findings, provided strict adherence to donor screening and evaluation protocols, the use of organ-cultured corneas from septic donors for DMEK does not appear to raise the risk for recipients and permits for expansion of the donor pool for corneal tissue.

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