See I, et al. - In view of the previous reports suggesting changes in U.S. methicillin-resistant Staphylococcus aureus (MRSA) strain epidemiology since the rise of USA300 MRSA, researchers sought to delineate invasive MRSA trends by strain type via assessing data from five CDC Emerging Infections Program sites conducting population-based surveillance and collecting isolates for invasive MRSA (ie, from normally sterile body sites), 2005–2013. For hospital-onset and healthcare-associated, community-onset BSIs, most notable reduction in USA100 incidence was observed. They also noted a reduction in USA300 incidence for hospital-onset BSIs. However, for healthcare-associated, community-onset or community-associated BSIs USA300 incidence did not significantly change.