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Trends in incidence and outcomes of pregnancy-related acute myocardial infarction (from a Nationwide Inpatient Sample database)

American Journal of Cardiology Jan 31, 2019

Tripathi B, et al. - Researchers used the 2005-2014 Nationwide Inpatient Sample (NIS) database to analyze trends in the incidence and outcomes of pregnancy-related acute myocardial infarction (AMI). They identified pregnancy related admissions and AMI by using International Classification of Disease-Ninth Revision (ICD-9). They also determined predictors of AMI during pregnancy by using simple logistic regression model. Over the study period, overall 43,437,621 pregnancy related hospitalization and 3,786 cases of AMI (86% ante-partum and 14% post-partum) were documented. Findings revealed a rise in the incidence of AMI between 2005 and 2014 with a concomitant decrease in mortality and resource utilization. The factors that significantly predicted AMI during pregnancy included higher age of pregnancy, black race, comorbidities such as hypertension, thrombophilia, diabetes mellitus, substance abuse, smoking, hyperlipidemia, heart failure, deep venous thrombosis (DVT), transfusion, fluid and electrolyte imbalance and postpartum complications such as hemorrhage, infection and depression.

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