Butler J, Yang M, Sawhney B, et al. - The present study was conducted to explore treatment patterns and clinical outcomes in commercially insured chronic heart failure and reduced ejection fraction (HFrEF) patients < 65 years old during 1-year periods before and after a worsening heart failure event (WHFE). Researchers carried out a retrospective claims analysis using the IBM MarketScan Commercial Database on HFrEF patients aged < 65 during the year before and after a WHFE, characterized as HF hospitalization or outpatient intravenous diuretic use. They evaluated treatment patterns, re-hospitalizations, health care resource utilization, and costs. Researchers enrolled a total of 4460 HFrEF patients with WHFE. The results of this study demonstrate that the use of HF medications elevated pre-WHFE but reduced post-WHFE, despite recurrent hospitalizations. These observations imply that age and insurance status may not totally explain the suboptimal treatment of HFrEF patients before and after a WHFE. Reasons for these trends need future research.