Kresoja KP, Lauten A, Orban M, et al. - Researchers performed this retrospective analysis to determine the effect of left‐sided heart failure (HF) types on results of transcatheter tricuspid valve edge‐to‐edge repair (TTVR). A composite outcome of all‐cause death and HF hospitalization at 12 months was the primary outcome. Experts found no difference in procedural success between HFpEF (HF with preserved ejection fraction) or HFrEF (HF with reduced ejection fraction) patients. A more frequent occurrence of the primary endpoint was reported in patients with HFrEF vs HFpEF. Lower mortality in relation to successful TTVR vs conservative therapy was observed in HFpEF patients, but not in HFrEF patients, after matching for age, EuroSCORE II, presence of a right ventricular lead and systolic pulmonary artery pressure. Based on these data, experts suggested the likely usefulness of TTVR as a treatment choice in patients with severe tricuspid regurgitation and HFpEF vs conservative therapy.