Schymik G, et al. – This study investigated the impact of a reduced left ventricular ejection fraction (EF) on the short– and long–term prognosis of patients undergoing transcatheter aortic valve implantation (TAVI), analyzing data from the Karlsruhe TAVI registry. Findings highlighted higher post–TAVI mortality for patients with a reduced EF, although excess comorbidity burden possibly contributed to this. It was advocated that a reduced EF should not be considered a contraindication for TAVI per se, but the additional presence of comorbidity suggests increased risk for these patients.