Total iron binding capacity (TIBC) is a potential biomarker of left ventricular remodelling for patients with iron deficiency anaemia
BMC Cardiovascular Disorders Jan 16, 2020
Chen Y, Wan J, Xia H, et al. - By performing this retrospective analysis, researchers searched for a potential biomarker for the myocardial remodelling in patients having iron deficiency (ID). Since limited patients having ID are recognized without iron deficiency anaemia (IDA), experts examined the link of total iron binding capacity (TIBC) and the left ventricular mass index (LVMI) in patients having iron deficiency anaemia. This inquiry was performed on 82 patients with IDA showing the diagnostic criteria for IDA. Of these, 65 produced documented LVMI values. The categorization of these patients into two groups was done according to abnormal LVMI (> 115 g/m2 in men and > 95 g/m2 in women). The abnormal LVMI group vs the control group exhibited increased levels of TIBC. According to the findings, there was an explicit link of TIBC with LVMI in patients with iron deficiency anaemia. In this population with IDA, TIBC was further confirmed as a contributor to abnormal LVMI incidence, in the logistic analysis.
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