Machado-Alba JE, et al. - Researchers conducted this retrospective study to determine the time elapsed from when a patient ≥ 65 years old is diagnosed with T2DM and starts antidiabetic treatment until a change in treatment is needed as well as the factors related to the change. This investigation was performed on individuals 65 years or older with a first-time diagnosis of T2DM, and these individuals were followed for 60 months until an addition or change was made to their antidiabetic drug regimen. Thirteen thousand five hundred seventy-three patients were identified with a mean age of 76.8 ± 7.7 years. In total, 9,144 individuals started treatment with a single antidiabetic drug, 4,146 started with two, and 282 started with three, particularly metformin (n = 10,858), sulfonylureas (n = 4,525), and insulins (n = 2,334). According to findings, most of the elderly adults diagnosed with T2DM after age 65 were treated with the appropriate medications. For more than half of the patients, therapy was modified. New antidiabetic drugs were infrequently introduced.