Cheng X, Yang N, Li Y, et al. - Given that the shape of the glucose response curve during an oral glucose tolerance test (OGTT) can anticipate β-cell function and insulin resistance, researchers conducted this retrospective study to verify the usefulness of the glucose response curve in a large Chinese population. In total, 9,059 OGTT (3-h tests) were categorized into either a monophasic or a multiphasic group based on the shape of the glucose response. The shape of the OGTT glucose response curve was 87.3% monophasic and 12.7% multiphasic. Compared with those in the monophasic group, individuals in the multiphasic group were younger. Compared with those in the multiphasic group, people in the monophasic group had significantly higher fasting plasma glucose, fasting insulin, and homeostasis model assessment of insulin resistance and impaired β-cell function. Overall, the authors concluded that in a large Chinese population, the monophasic OGTT glucose response curve could reflect impaired β-cell function.