The role of prognostic factors in salivary gland tumors treated by surgery and adjuvant radio- or chemoradiotherapy – A single institution experience
Cancer Management and Research Feb 17, 2020
Kordzińska-Cisek I, et al. - Researchers conducted the study for analyzing the treatment outcomes and identification of the risk factors influencing the prognosis in individuals with tumors of large salivary glands subjected to adjuvant radio- or radiochemotherapy. One hundred twenty-six patients with local stage large salivary gland cancer who were treated surgically with adjuvant radio- or radiochemotherapy were included. Inoperable patients, patients with distant metastases, patients in a poor general condition and patients with contraindications to adjuvant treatment were excluded. Data reported that 5-overall survival, cancer-specific survival, relapse-free survival, and local relapse-free survival, respectively, were 55%, 68%, 60% and 73% during a 44-month follow-up. According to results, the most important prognostic factors in these individuals were TNM grade, histopathological type, patient’s condition, the radicality of the procedure, technique and dose of radiotherapy.
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