The prognostic value of lncRNA SNHG1 in cancer patients: A meta-analysis
BMC Cancer Aug 11, 2019
Dong B, Chen X, Zhang Y, et al. - In this quantitative meta-analysis, researchers looked at the prognostic significance of small nucleolar RNA host gene 1 (SNHG1) in various cancers. They comprehensively explored PubMed, Web of Science, Embase, ISI Web of Knowledge, Cochrane Library, BioMed Central, Springer, ScienceDirect, and three Chinese databases: CNKI, Weipu and Wanfang, up to March 20, 2018, to identify relevant articles published in English and Chinese. They found a link between promoted SNHG1 expression and tumor progression. In both digestive system and non-digestive system cancer patients, a significantly unfavorable association of elevated long noncoding RNA SNHG1 and overall survival (OS) was identified in stratified analyses. Poor OS was reported in patients with general tumors in relation to increased SNHG1. Based on the findings, the possible utility of SNHG1 as a prognostic biomarker was suggested in this study.
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