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The prognostic value of initial serum lactate for survival in postcardiac arrest patients undergoing cardiac catheterization

Catheterization and Cardiovascular Interventions Feb 19, 2021

Rosenberg RD, Guo CYC, Chatterjee S, et al. - Whether serum lactate has prognostic value on survival in patients postcardiac arrest, was determined herein. A retrospective analysis was performed with 384 patients who were referred urgently to the cath lab after cardiac arrest between January 2014 and September 2018, 50 with prior arrest. Coronary intervention was received by 66%. The study sample had a mean age of 57 years, 34% were women, 40% had a history of coronary artery disease, and 94% were intubated at the time of cardiac catheterization. In survivors vs nonsurvivors, mean lactate concentration was 4.7 ± 3.8 and 9.8 ± 4.7 mmol/L, respectively. When split into tertiles based on serum lactate (< 4.5, 4.5–9, 9 mmol/L), survival to discharge was reported to be 75, 29.4, and 17.6%, respectively. In‐hospital mortality was independently predicted by initial serum lactate and age. Based on these findings, experts suggest the usefulness of routine measurement of serum lactate, which is an available laboratory test, for identifying patients carrying a risk for a poor outcome in a population of patients receiving cardiac catheterization post-cardiac arrest.

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