The prognostic nutritional index might predict clinical outcomes in patients with idiopathic dilated cardiomyopathy
Nutrition, Metabolism & Cardiovascular Diseases Oct 23, 2019
Chen XL, Wei XB, Huang JL, et al. - Researchers assessed the prognostic nutritional index (PNI) as a predictor of adverse outcomes in patients with idiopathic dilated cardiomyopathy. Retrospectively included 1,021 consecutive cases were analyzed and categorized into three groups depending on admission PNI tertiles: < 41.7 (n = 339), 41.7–47.3 (n = 342), > 47.3 (n = 340). They assessed the link of PNI with in-hospital major adverse clinical events (MACEs) and mortality during follow-up. From the lowest to the highest PNI tertile, reduction in in-hospital mortality and MACEs was noted. For predicting in-hospital MACEs, the optimal cut-off value of PNI was estimated to be 44.0 (area under the curve: 0.689; 95% confidence interval: 0.626–0.753). In this patient population, PNI was identified as an independent risk factor for in-hospital MACEs and all-cause death at a median follow-up of 27 months. Therefore, it may be thought of as a tool for risk evaluation.
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