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The product of fasting plasma glucose and triglycerides improves risk prediction of type 2 diabetes in middle-aged Koreans

BMC Endocrine Disorders Jun 06, 2018

Lee JW, et al. - Using the Korean Genome and Epidemiology Study, the researchers assessed whether fasting plasma glucose (FPG) or triglyceride (TG)-related indices can improve the predictive ability of a diabetes risk model for middle-aged Koreans. Seven thousand, seven hundred eight people aged 40 to 69 years without diabetes were eligible for the current study. Findings revealed that adding either product of fasting glucose and triglyceride (TyG index) or FPG into the basic risk model for type 2 diabetes mellitus (T2DM) increases its prediction and reclassification ability. It was noted that TyG index was a more robust T2DM predictor in the stratified sex and fasting glucose level compared to FPG. For identification of people at high risk for T2DM in practice, TyG index should be considered as a screening tool.
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