Hovanesian JA, et al. - In this prospective, open-label, multicenter analysis, researchers sought to compare spectacle independence, patient-reported outcomes (PROs), and dysphotopsia after multifocal intraocular lens (IOL) implantation with the AcrySof PanOptix trifocal or the ReSTOR +2.5/3.0 D or ReSTOR +2.5 D mini-monovision multifocal IOL. Participants in the study were 59 patients, mean age 69 ± 9.6 years. Findings revealed that there was a higher percentage of patients who underwent femtosecond laser-assisted cataract surgery in the PanOptix cohort (n = 52, 88%) than in the 2.5 mini-monovision cohort (n = 57, 56%) or the 2.5/3.0 cohort (n = 18, 22%). The AcrySof PanOptix trifocal offers significantly higher spectacle independence across all measured activities than the AcrySof ReSTOR multifocal IOLs.