Ito H, et al. – Here the authors presented the hypothesis that the global left ventricular (LV) afterload, including valvular and arterial impedance, could influence LV reverse remodeling after aortic valve replacement (AVR). Investigations displayed that the postoperative valvuloarterial impedance (Zva) was significantly associated with LV mass regression after AVR. Hence, maintaining low global LV afterload following AVR might enhance LV reverse remodeling.