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The epidemiology of gastric cancers in the era of Helicobacter pylori eradication: A nation-wide cancer registry-based study in Taiwan

Cancer Epidemiology, Biomarkers & Prevention Aug 02, 2019

Chang JS, Kuo SH, Chu PY, et al. - In order to gain more clarity regarding the epidemiology of gastric lymphoma, which is related to Helicobacter pylori (H.P.), and other rare subtypes of gastric cancer, researchers performed a comprehensive assessment in Taiwan to analyze incidence trends from 1996 and 2013 as well as the survival of gastric cancer by histologic subtype. From 1996 to 2013, a fall in the incidence of all gastric cancers, from 15.97 per 100,000 to 11.57 per 100,000, respectively, was reported in Taiwan. Adenocarcinoma was identified as the most frequent histologic subtype, followed by lymphoma, and sarcoma (mainly gastrointestinal stromal tumor) in the order of frequency. Sarcoma showed the best survival, followed by lymphoma, neuroendocrine tumor and adenocarcinoma. Better survival was generally seen among women vs men. A significant decline was noted in the incidence of adenocarcinoma, from 13.56 per 100,000 in 1996 to 9.82 per 100,000 in 2013, whereas, no reduction was evident in the incidences of mucosa-associated lymphoid tissue lymphoma and diffuse large B cell lymphoma. Overall, findings revealed diverging trends for the incidence of adenocarcinoma and lymphoma, both of which are related to H.P.
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