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The effects of aerobic exercise on N-terminal pro B-type natriuretic peptide and cardiopulmonary function in patients with heart failure: A meta-analysis of randomised clinical trials

Heart, Lung, and Circulation Jul 16, 2020

Santoso A, Maulana R, Alzahra F, et al. - This meta-analysis was conducted to determine how N-terminal pro B-type natriuretic peptide (NT-pro-BNP) levels and cardiopulmonary function are impacted by aerobic exercise in patients with heart failure (HF). Relevant randomised controlled trials (RCTs) were identified by systematically exploring databases (Pubmed, EMBASE, Medline, Cochrane Central Registry, and Scopus). Overall thirteen (13) RCTs with 1,503 patients and 1,494 controls were analyzed. Per findings, patients with HF showed improvement in NT-pro-BNP, ventilatory efficiency, aerobic capacity, maximal workload, and the left ventricular function, as a result of performing aerobic exercise.

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