Tominaga H, et al. - Via a non-randomized controlled trial of 13 patients who underwent lumbar fusion surgery, the researchers targeted to discover the effect of ultraviolet photofunctionalization of titanium instrumentation (a widely used in the field of orthopedics because of its high osteoconductivity) used in lumbar fusion. No significant difference between the degree of osteosclerosis (as assessed by the density) around the treated vs untreated cages at any time point was noticed. Further, in comparison to the ratio of carbon attachment to titanium instrumentation as previously recorded in the dentistry field, the ratio of carbon attachment of the titanium cages was considerably less. Hence, in spine surgery, the outcome of ultraviolet photofunctionalization of titanium instrumentation is questionable in the present scenario. Therefore, the biological aging of the titanium might be affected by variations in the manufacturing process of orthopedics instrumentation vs dentistry instrumentation.