Kudesia R, et al. - Researchers evaluated the effect of female body mass index (BMI) on in vitro fertilization (IVF) cycle outcomes. They conducted a retrospective cohort study including 51,198 women who initiated their first autologous IVF cycle in 13 fertility centers in the USA between 2009 and 2015. For multiple outcomes, including cycle cancellation, oocyte and embryo counts, and ongoing clinical pregnancy (OCP), a BMI above the normal range was an independent negative prognostic factor. In women with class-II/III obesity, ovulatory dysfunction, or PCOS, these negative outcomes were most profound.