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The development and validation of a multivariable prognostic model to predict foot ulceration in diabetes using a systematic review and individual patient data meta-analyses

Diabetic Medicine Aug 17, 2018

Crawford F, et al. - Using all available individual patient data from cohort studies conducted worldwide, researchers intended to derive and validate a prognostic model of independent risk factors for foot ulceration in diabetes. A systematic review and meta-analysis of individual patient data was conducted from 10 cohort studies of risk factors in the prediction of foot ulceration in diabetes. They found that this prognostic model of only 3 risk factors (a history of foot ulceration, an inability to feel a 10 g monofilament and the absence of any pedal pulse) compares favourably with more complex approaches to foot risk assessment recommended in clinical diabetes guidelines.
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