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The bacteriome at the onset of type 1 diabetes: A study from four geographically distant African and Asian countries

Diabetes Research and Clinical Practice Aug 22, 2018

Cinek O, et al. - Researchers conducted the study for analyzing the stool bacteriome in children after the onset of type 1 diabetes (T1D) along with age- and place-matched control subjects from four geographically distant African and Asian countries. For this investigation, samples were collected from 73 children and adolescents shortly after T1D onset (Azerbaijan 19, Jordan 20, Nigeria 14, Sudan 20) and 104 matched control subjects of similar age and locale. The data presented in this work showed a significant positive relationship with T1D for the genus Escherichia. On the other hand, Eubacterium and Roseburia, two genera of class Clostridia, phylum Firmicutes, were inversely related to T1D. It was noted that some type of distortion of the gut bacteriome seems to be a global feature of T1D. The findings for four distant populations add new candidates to the existing list of bacteria.
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