Martin TCS, Hill LA, Tang ME, et al. - In this study, the effectiveness of ART regimens that included the coadministration of tenofovir alafenamide (TAF) and rifabutin (RFB) was ascertained. Persons with HIV (PWH) who received TAF-RFB coadministration for ≥1 month were retrospectively distinguished. The primary endpoint included the maintenance of HIV viral load < 200 copies/ml (cpm) for those already on HIV therapy at RFB initiation or suppression of viral load to < 200 cpm for those with unsuppressed HIV viral load prior to TAF-RFB coadministration. The data implies that TAF-RFB coadministration may be effective despite concerns that RFB could decrease TAF absorption.