Lascarrou JB, Merdji H, Le Gouge A, et al. - Among patients with coma who had been admitted to the intensive care unit following resuscitation from cardiac arrest with nonshockable rhythm, researchers compared moderate therapeutic hypothermia (33°C during the first 24 hours) vs targeted normothermia (37°C) in this open-label, randomized, controlled trial. Survival with a favorable neurologic outcome, evaluated on day 90 following randomization with the use of the Cerebral Performance Category (CPC) scale, was the primary outcome. A CPC score of 1 or 2 defined a favorable neurologic outcome. Findings revealed that the use of moderate therapeutic hypothermia at 33°C for 24 hours vs targeted normothermia in patients with coma who had been resuscitated from cardiac arrest with nonshockable rhythm resulted in a higher percentage of patients who survived with a favorable neurologic outcome at day 90.