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T1 mapping cardiac magnetic resonance imaging frequently detects subclinical diffuse myocardial fibrosis in systemic sclerosis patients

Seminars in Arthritis and Rheumatism Jun 26, 2019

Poindron V, et al. - Via a study on 72 patients fulfilling the ACR/EULAR classification criteria for systemic sclerosis (SSc, an immune-mediated systemic rheumatic disease), the researchers ascertained the prevalence of cardiac involvement by cardiac magnetic resonance imaging (CMR) native T1 mapping and its correlation with echocardiography data and non-cardiac signs. No cardiac symptoms, normal echocardiography, and CMR left ventricular ejection fraction, and no Late Gadolinium Enhancement was observed in 36% of patients with elevated T1 (ET1). In 50% of patients with SSc, native T1 mapping identified left ventricular ET1 (potential diffuse myocardial fibrosis) and a normal conventional screening including standard CMR of a third of them was observed. Hence, further studies to strengthen the benefit of use of native T1 mapping as a part of routine follow up to detect earlier pejorative cardiac involvement in SSc patients is suggestive.
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