Systematic review and meta-analysis of prevalence in post-stroke neurocognitive disorders in hospital-based studies
Dementia and Geriatric Cognitive Disorders Dec 05, 2018
Barbay M, et al. - Researchers evaluated the prevalence of total, mild, and major post-stroke neurocognitive disorders (post-stroke NCD) through a meta-analysis based on a systematic review of hospital-based studies and determined factors affecting this prevalence. On the basis of a systematic literature search, hospital-based studies published between January 1990 and September 2015 reported the prevalence of total, mild and major post-stroke NCD diagnosed using specified criteria. They found that 53.4% of patients surviving a stroke experience post-stroke NCD, corresponding to mild post-stroke NCD in 36.4% and major NCD in 16.5% of cases. Data reported that the prevalence of major post-stroke NCD was influenced mainly by age. In two-thirds of cases and major post-stroke NCD in one-third of cases, more than half of stroke survivors experience post-stroke NCD which corresponds to mild post-stroke NCD. Findings revealed that harmonization of stroke and cognitive score thresholds is urgently required to better estimate post-stroke NCD prevalence, particularly mild post-stroke NCD.
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