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Sustained inflation vs standard resuscitation for preterm infants: A systematic review and meta-analysis

JAMA Feb 14, 2020

Foglia EE, te Pas AB, Kirpalani H, et al. - Researchers sought to perform a systematic review and meta-analysis of sustained inflation vs intermittent positive pressure ventilation and continuous positive airway pressure for the prevention of hospital mortality and morbidity for preterm infants. They searched MEDLINE (through PubMed), Embase, the Cumulative Index of Nursing and Allied Health Literature, and the Cochrane Central Register of Controlled Trials through June 24, 2019. Nine studies were selected including a total of 1,406 infants. No difference was found in the risk of the primary result of death before hospital discharge, and there was no evidence of efficacy for sustained inflation to prevent secondary outcomes. The results do not advocate the routine use of sustained inflation for preterm infants after birth.
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