Successful reperfusion with endovascular therapy has beneficial effects on long-term outcome beyond 90 days
Cerebrovascular Diseases Apr 12, 2019
Todo K, et al. - By retrospectively analyzing a database of consecutive patients with acute ischemic stroke receiving endovascular therapy in four centers between April 2006 and March 2016, researchers analyzed how successful reperfusion (ie, modified thrombolysis in cerebral infarction score of 2b or 3) might be linked with a temporal change in modified Rankin Scale (mRS) score from 90 days to 1 year following endovascular therapy in order to assess the long-term effects beyond 90 days. The current study included a total of 268 patients. In patients with successful reperfusion, the rate of patients who improved tended to be higher vs patients with unsuccessful reperfusion. Likewise, the rate of deterioration was lower in patients with successful reperfusion vs unsuccessful reperfusion. Findings revealed that successful reperfusion was related to improvement and deterioration after confounders adjustment, regardless of the 90-day mRS score. Overall, the investigators concluded that beneficial effects beyond 90 days following stroke are seen with successful reperfusion.
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