Duman R, et al. - Authors evaluated the ganglion cell complex (GCC) thickness, retinal nerve fiber layer (RNFL) thickness and optic disk features in the affected eyes (AE) and unaffected fellow eyes (FE) of subjects with unilateral nonarteritic anterior ischemic optic neuropathy (NAION) and compared with healthy control eyes (CE) using spectral domain-optical coherence tomography (SD-OCT). Findings demonstrated a significant decrease in the GCC and RNFL thickness at late stages of NAION, in both AE and FE vs CE, thereby suggesting that in FE, despite lack of obvious visual symptoms some subclinical structural changes could occur. Moreover, no significant difference in optic disk features between the CE and FE was noted. The acquired enlargement of cupping after the onset of NAION was supported by significantly greater optic disk cupping in the AE compared with both FE and CE.