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Stroke and dementia risk: A systematic review and meta-analysis

Alzheimer's & Dementia Oct 24, 2018

Kuźma E, et al. - Researchers studying the connection between stroke and all-cause dementia risk through a systematic review and meta-analysis. For this investigation, Medline, PsycINFO, and Embase were searched for studies assessing prevalent or incident stroke vs a no-stroke comparison group and the risk of all-cause dementia. Thirty-six studies of prevalent stroke (1.9 million participants) and 12 studies of incident stroke (1.3 million participants) were identified in this analysis. It was noted that the pooled hazard ratio for all-cause dementia was 1.69 for prevalent stroke whereas the pooled risk ratio was 2.18 for incident stroke. For all-cause dementia, stroke is a strong, independent, and potentially modifiable risk factor.
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