Zweerink A, et al. - Researchers compared different strain parameters with respect to their predictive performance, and assessed the results per imaging technique to predict cardiac resynchronization therapy (CRT) response. In 27 prospectively enrolled patients who underwent cardiovascular magnetic resonance (CMR) and echocardiographic examination before CRT implantation, they performed strain analysis in circumferential and longitudinal orientations. These patients were followed for 12 months, after which echocardiographic change in left ventricular end-systolic volume was assessed to measure CRT response. They found that, regardless of assessment technique, the only parameter that demonstrated a consistent good relation to reverse remodeling after CRT was end-systolic septal strain. Clinicians can use any available strain imaging technique to get this measurement, which offers predictive value in addition to current guideline standards.