Status of prehospital delay and intravenous thrombolysis in the management of acute ischemic stroke in Nepal
BMC Neurology Jul 15, 2019
Nepal G, et al. - In Nepal, researchers assessed the status of prehospital delay and thrombolysis in 228 patients. Between August 2017 and August 2018, they prospectively gathered data from patients aged > 18 years in the emergency department (ED) with symptoms and neuroimaging findings consistent with an ischemic stroke. To evaluate the degree of disability and severity of stroke respectively, Modified Rankin scale and National Institute of Health stroke scale were utilized. According to results, only 20% of patients came for thrombolysis in the time frame and 13.15% got thrombolysis. Early arrival was linked to onset at daytime, stroke symptoms facial deviation and speech disturbances, stroke identification, rushing to ED after onset of symptoms, awareness of stroke treatment, direct presentation, distance less than 20 km, and education above high school. Heavy traffic, earnings below 1,000 USD per year, and diabetes mellitus were linked to delayed arrival to ED. Findings suggested that community-based intervention to raise awareness, setting up comprehensive stroke centers, training professionals, enabling better emergency services, setting up telestroke facilities, and encouraging the use of low-cost tenecteplase as an option to alteplase can assist enhance stroke patient care in Nepal.
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