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Smartphone-enabled video-observed vs directly observed treatment for tuberculosis: A multicentre, analyst-blinded, randomized, controlled superiority trial

The Lancet Mar 27, 2019

Story A, et al. - In this multicentre, analyst-blinded, randomized controlled superiority trial, researchers examined the outcomes of smartphone-enabled video-observed therapy (VOT) vs directly observed treatment (DOT) for tuberculosis. They observed 58% of subjects with a history of homelessness, imprisonment, drug use, alcohol problems or mental health problems. They noticed an achievement of ≥80% scheduled observations successfully completed during the first 2 months among candidates on VOT when compared with 35 (31%) of 114 on DOT. They noted that 77% of 101 subjects on VOT achieved the primary outcome vs 63% of 56 on DOT in the restricted analysis. They overall suggested VOT a more efficient strategy to observation of tuberculosis treatment as compared to DOT.
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