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Site-level variability in 30-day patient outcomes after transcatheter mitral valve repair in the United States

Circulation: Cardiovascular Quality and Outcomes Dec 10, 2020

Malik AO, Chhatriwalla AK, Saxon J, et al. - To determine real-world site-level variability in health status outcomes for transcatheter mitral valve repair (TMVr), as well as to explore factors related to this variability, researchers undertook this study wherein they used the Transcatheter Valve Therapy Registry in order to analyze all patients receiving TMVr with MitraClip between November 2013 and March 2019. They assessed site-level variability in 30-day alteration in Kansas City Cardiomyopathy Questionnaire Overall Summary, by computing the median odds ratio from a hierarchical logistic regression model, with ≥ 20-point improvement as the dependent variable. Findings demonstrated that across sites, patients’ achievement of health status benefits from TMVr differed moderately, and patient’s baseline health status accounted for the largest proportion of this difference. This highlights that patient selection is important in supporting more consistent health status advantage from TMVr.

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