Nunome T, et al. - Authors gauged the efficacy of an intravitreal triamcinolone acetonide injection (IVTA) combined with cataract surgery for diabetic macular edema (DME) resistant to anti-vascular endothelial growth factor (anti-VEGF) therapy. As per data, at 24 weeks after the treatment, the visual acuity improved significantly from 0.49 ± 0.30 logMAR units to 0.35 ± 0.33 logMAR units. A significant decrease in CRT from 435.1 ± 112.3 μm to 350.8 ± 123.3 μm at 12 weeks after the treatment was seen. They noted the retinal sensitivity threshold to improve significantly from 18.2 ± 4.3 dB to 20.4 ± 3.8 dB at 4 weeks after the treatment. For successful treatment of eyes with DME refractive to anti-VEGF therapy, IVTA combined with cataract surgery was seen to be effective.