Wettersten N, Horiuchi Y, van Veldhuisen DJ, et al. - Researchers examined the predictive value of serum neutrophil gelatinase-associated lipocalin (sNGAL) or urine NGAL (uNGAL) vs creatinine for short-term outcomes in acute heart failure (AHF). An international, multicentre, prospective cohort of 927 patients with AHF (mean age: 69 years; 62% males) was assessed for admission and peak values of sNGAL, uNGAL and uNGAL/urine creatinine (uCr) ratio and admission and peak serum creatinine (sCr). The composite endpoints were death, initiation of renal replacement therapy, heart failure (HF) readmission and any emergent HF-related outpatient visit within 30 and 60 days, respectively. One hundred six patients and 154 patients experienced the composite endpoint within 30 and 60 days, respectively. In this work, serum NGAL outperformed uNGAL, however, neither of these was identified as superior to admission or peak sCr for predicting adverse events.