Novotny V, Khanevski AN, Bjerkreim AT, et al. - Because patients with acute cerebral infarcts in multiple arterial territories (MACI)—defined as ≥ 2 acute cerebral ischemic lesions in ≥ 2 arterial cerebral territories—constitute a substantial portion of the stroke population, researchers compared patients with MACI vs those with acute cerebral infarct(s) in a single arterial territory. A total of 3,343 patients with diffusion-weighted imaging-confirmed acute cerebral infarcts were analyzed. In all, 311 patients met inclusion criteria for MACI. In-hospital complications were more frequent in patients with MACI, which may adversely affect clinical and functional outcomes in the short term. During hospitalization, closer follow-up of patients with MACI may prevent such events and negative progression.