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Sex differences in the long-term prognosis of dilated cardiomyopathy

Canadian Journal of Cardiology Jun 06, 2019

Cannatà A, et al. - Using a large cohort, researchers determined the long-term prognostic role of gender in patients with dilated cardiomyopathy (DCM). Overall 1,113 patients were prospectively enrolled. Using a sample of 586 patients, a propensity score matching analysis was undertaken to determine the influence of sex. All-cause mortality/heart transplantation (HTx)/ventricular assist device (VAD); cardiovascular mortality/HTx/VAD; sudden cardiac death or malignant ventricular arrhythmias were all assessed by estimating univariable and multivariable Cox models and competing risk analyses on both cohorts. They found more favorable long-term outcomes among women than men in this patient population suffering DCM. They also identified gender as a significant independent factor, especially for cardiovascular outcomes.

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