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Sex differences in outcome after endovascular stroke therapy for acute ischemic stroke

Stroke Aug 21, 2019

Sheth SA, Lee S, Warach SJ, et al. - In this investigation involving 389 patients, researchers analyzed the impact of sex on outcome after endovascular stroke thrombectomy in acute ischemic stroke, including lifelong disability outcomes. Study participants treated with the Solitaire stent retriever in the combined SWIFT (Solitaire FR With the Intention for Thrombectomy), STAR (Solitaire FR Thrombectomy for Acute Revascularization), and SWIFT PRIME (Solitaire FR With the Intention for Thrombectomy as Primary Endovascular Treatment) cohorts were analyzed. No differences were found between females compared with males in presenting deficit severity, occlusion location, presenting infarct extent, rate of substantial reperfusion, onset to reperfusion time. Despite higher age (69 vs 64) and a higher atrial fibrillation rate (45% vs 30%), women experienced comparable functional outcomes and higher years of optimal life (disability-adjusted life year) after intervention vs men.
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