Lei Z, et al. - The researchers carried out a systematic review and meta-analysis to assess the association between the serum uric acid (SUA) level and outcome of patients with ischemic stroke. By Begg’s test, publication bias was detected. Included were 15 studies with a total of 12,739 stroke cases. The data presented in this work showed a significant positive link between SUA level and the outcome of ischemic stroke, with higher SUA levels correlating with a significantly better ischemic stroke outcome. Furthermore, the pooled estimate of patients with a modified Rankin Scale score ≤2 at 90 days also exhibited a positive connection, as did patients receiving thrombolytic therapy.