Chang YC, et al. - Researchers examined the link between serum sclerostin levels and carotid–femoral pulse wave velocity (cfPWV) among 105 hypertensive patients. Two groups were formed based on cfPWV values: the high arterial stiffness group including patients with cfPWV values of > 10 m/s, and the low arterial stiffness group including patients with cfPWV values of ≤ 10 m/s. Commercially available enzyme-linked immunosorbent assays were used to quantify serum sclerostin and Dickkopf-1 (DKK1) levels. Findings revealed a positive correlation of serum sclerostin level, but not of DKK1, with cfPWV values. After adjusting for significant confounders, serum sclerostin level was identified as an independent predictor of arterial stiffness in hypertensive patients.