Pathela P, Crawley A, Weiss D, et al. - The US epicenter of the Spring 2020 COVID-19 pandemic was New York City (NYC). Based on a large serosurvey of adult NYC residents (May 13-July 21, 2020), researchers sought to report on the seroprevalence of SARS-CoV-2 infection and correlates of seropositivity immediately after the first wave. Findings revealed infection of just under one-quarter of NYC adults in the first few months of the COVID-19 epidemic. Seroprevalence was noted to be high (>30%) among Black and Hispanic individuals, people from high poverty neighborhoods, and people in health care or essential worker industry sectors. Seropositivity was observed in correlation with COVID-19 symptom history. Following were the other risk factors: gender, age, race/ethnicity, residential area, employment sector, working outside the home, contact with a COVID-19 case, obesity, and increasing numbers of household members. Researchers suggest necessity for effective interventions for at-risk groups during ongoing transmission in view of the observed disparities in infection risk.