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Seroprevalence of measles, mumps and rubella and genetic characterization of mumps virus in Khartoum, Sudan

International Journal of Infectious Diseases Nov 28, 2019

Adam O, et al. - Given that currently, mumps and rubella vaccines are used in Sudan, researchers sought to ascertain the seroepidemiology of measles, mumps, and rubella (M.M.R), as well as information about circulating mumps virus genotypes. They tested dried blood spot samples collected from 294 children, 153 adults from the general population and 241 healthcare workers (HCWs) from Khartoum in 2015/2016. The seroprevalence of M.M.R antibodies was 93.5%, 63.6% and 55.8% among children, while among adult volunteers, it was 93.5%, 90.8%, and 94.1% and among HCWs, it was 99.2%, 97.1%, and 97.9%, respectively. Findings support the efficacy of the current measles vaccination program. As per the study, active wild-type rubella and mumps virus circulation was evident. Compared with other adults, healthcare workers were significantly more exposed. For the first time, the identification of mumps virus genotype C in Sudan was done.
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