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Safety and efficacy of baroreflex activation therapy for heart failure with reduced ejection fraction: A rapid systematic review

ESC Heart Failure Jan 29, 2020

Schmidt R, et al. - Researchers performed a rapid systematic review of clinical studies in order to collect and evaluate the available data in the literature concerning the safety and efficacy of baroreflex activation therapy (BAT) in heart failure with reduced ejection fraction (HFrEF) patients. Searching PubMed, EMBASE, CENTRAL, Scopus, and Web of Science using Mesh and free terms for heart failure and BAT, they screened 441 citations; of these, they included 10 publications (three were only conference abstracts), reporting data from three studies. Findings suggest that a well-trained multi-professional team performs the procedure safely. All the included studies described improvements in clinical outcomes. However, no conclusive statements on the efficacy of BAT for HFrEF were made as there were several limitations.
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