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Risk profiling of soil-transmitted helminth infection and estimated number of infected people in South Asia: A systematic review and Bayesian geostatistical Analysis

PLoS Neglected Tropical Diseases Aug 14, 2019

Lai YS, Biedermann P, Shrestha A, et al. - As hundreds of millions of people are infected with soil-transmitted helminths (Ascaris lumbricoides, hookworm, and Trichuris trichiura) in South Asia, researchers examined high-resolution risk profiles and estimated the number of people infected across four mainland countries (ie, Bangladesh, India, Nepal, and Pakistan) of South Asia. For A. lumbricoides, hookworm, and T. trichiura, they identified a total of 536, 490, and 410 georeferenced surveys, respectively, from PubMed and ISI Web of Science. As per estimates, nearly one-quarter of the South Asia population was infected with at least one soil-transmitted helminth species in 2015. The predominant species was A. lumbricoides. The northeastern part and some northern areas of the study region and the southern coastal areas of India displayed moderate to high prevalence (>20%) of any soil-transmitted helminth infection. For the school-age population needing preventive chemotherapy, the annual treatment requirements were estimated at 165 million doses.

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